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8/14/20 5:31PM
Re: what's the right multiple
16
I'm a lot more uncertain on the name due to the pandemic and the lost year of sales. So, I think you are right about the 15X being too high. I do think that competition
My opinion has shifted on the name due to the pandemic. A lots year of sales, plus a delay in the CCH rollout materially affect the upside due to the patent expiration. The rotating characters... login to read the rest
Given there's roughly seven years to patent expiration, why is 15x the right multiple in the base case? Is the assumption there is a durable revenue stream post patent expiration because its a biologic?
Despite a weird downtick to end the day, BSTc reported excellent earnings after the close and now has almost $106 million in cash on the books. Crazy strong cash generation also with the good news
One more point, is that with today's numbers, I can now make a pretty compelling case that peak Xiaflex sales without cellulite should hit $1 billion. With an 10.5% royalty rate, that would give BSTC,
Endo Pharma just reported blowout Xiaflex sales up 27% year over year and 23% sequentially to $101.5 million. Xiaflex is now on an annualized run rate of sales over $400 million. Phenomenal growth and great
Hi - thanks for the interesting writeup. Is it your assumption that if approval for cellulite goes through that it will be a cash pay market?
i realize of course it may be silly to think
Re: Probability of approval and duration of patent expiration.
6
From what I have read, the FDA may not want an extension on a biological if there is no real change to the drug, because of political pressure to keep drug prices down. That being... login to read the rest
Probability of approval and duration of patent expiration.
Interesting situation and good write-up. Could you please give more information on why it is unlcear if the label extension to cellulite will result in an extension of the patent which expires 2028? What typically... login to read the rest
There are all kinds of jokes people can make for sure. All joking aside the drug is well tolerated if done correctly and is the only approved pharmaceutical treatment.
1.8% of the people that have Peyronie's disease... login to read the rest
Quarterly injections to the penis?! And my wife is wondering why I'm walking around the kitchen hunched over now.
No disrespect to Issambres. Very interesting idea. Risk-reward definitely appears asymmetric.
"Xiaflex is a derivative of chemicals that the clostridium bacteria produce to invade the tissues they infect. The chemical, known as collagenase, breaks down the collagen in cell walls that puts up a defense against... login to read the rest
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